Is an acute infectious disease affecting many species of domestic and wild mammals including humans, the developing endemic sporadic- produced by Clostridium piliform characterized clinically and pathologically by digestive disorders and hepatitis necrotizing enterocolitis. Are receptive primarily rodents and fangs, mouse, rat, hamster, guinea pig, rabbit, dog, cat, coyote, fox, leopard, then horses, cattle, rhesus monkeys and man. The sources of infection are the rodents sick and those with unapparent infection, feed, water and objects contaminated with residues from them. The incubation period in infected conditions, natural is not known, the disease progresses superacute, acute or chronic. Superacute shape, common among foals, muskrats and mice evolve without overt clinical symptoms, the animals were found dead or comatose. Rarely seen in some specimens, apathy, loss of appetite, and diarrhea. Death occurs after a few hours to 1-2 days after onset. The acute form, the most common, serious deterioration is manifested by the general condition, depression, anorexia, hyperthermia unsteady, mucosal congestion and foals jaundice, diarrhea and sores seizures followed by death. In some animals, especially rabbits, muskrat and fox, watery diarrhea are observed, often hemorrhagic, sometimes in the form of faecal occult blood, which is not present in laboratory animals. Chronic form is rare and develops symptoms of the acute form, but mitigated without bloody diarrhea, plus progressive weakening.
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